Abstract: In recent years, numerous green building design concepts have been proposed to promote the sustainable development of cities and society, particularly strategies that integrate wind energy harvesting devices into building structures. However, the effects of such harvesting devices on wind load characteristics of the buildings have not yet been fully investigated. To this end, a novel green building design, namely three connected high-rise buildings integrated with a vertical-axis wind turbine, is adopted as the subject of this study. Based on extensive wind tunnel tests, this study thoroughly analyzes base moment coefficients of three connected high-rise buildings integrated with a vertical-axis wind turbine under three typical wind directions, considering different wind turbine integration directions, rotational directions, and rotational speeds. Furthermore, the distribution of wind pressure coefficients on building surfaces is used to support some mechanism analyses. The results show that the integration of the vertical-axis wind turbine has a minor influence on mean base moment coefficients of the buildings, which only decrease slightly in most cases. However, for the downstream buildings under the wind directions of 90° and 180°, the absolute values of mean base moment coefficients in the y-direction are significantly reduced. It is worth noting that the integration of the vertical-axis wind turbine increases fluctuating base moment coefficients of the buildings, especially for the wind directions of 90° and 180°, where fluctuating base moment coefficients in the y-direction reach high peak values when the tip-speed ratio of the vertical-axis wind turbine is low. These findings have significant implications for future designs focused on sustainability and also provide references for the wind-resistant design of high-rise buildings with similar designs.