Abstract: To accurately and efficiently simulate the structural responses to a detonation shock, and provide technical support for engineering applications in the fields of detonation wave propagation and damage assessment, etc., a numerical simulation platform for partitioned fluid-structure interaction under the condition of a detonation shock has been developed. The detonation and wave propagation are modeled based on a multiphase compressible flow library blastFoam in OpenFOAM. At the same time, the structural response is simulated by the deal.Ⅱ finite element library. Modules for solving fluid and structure are integrat by adapting the coupling library preCICE. The numerical simulation of the motion of a 3D vertical wall under a high-explosive detonation is carried out to verify the correctness of the platform. The numerically obtained detonation process is consistent with the documented detonation wave propagation process. The platform has a good parallel scalability. For a case with 5.1 million mesh cells, the speedup ratio with 256 processor cores is 178, yielding a parallel efficiency of 69.5%. Overall, by integrating various open source software, a partitioned fluid-structure interaction simulation platform for the structural responses to a detonation shock is realized, which has important practical significance for many engineering applications.