Abstract: Based on CARDC hypersonic numerical simulation platform Chant-2.0, applications of γ-Re_θ model to hypersonic boundary layer transition are investigated preliminarily. The transition onset and length are predicted by solving two transport equations for turbulence intermittency factor and momentum thickness Reynolds number. Firstly, γ-Re_θ transition model using local correlation functions is calibrated through four cases of low speed flat flows, and in the process freestream turbulence intensities have a wide range from low level natural transition to high level bypass transition. Then, taking account of flow properties of hypersonic boundary layer, the pressure gradient function used in the transition model's Re_θt correlation is properly modified for high Mach number flows. Finally, by adopting the new model functions, hypersonic boundary layer transitions of flat and sharp cone are calculated and compared with referrence data. The simulation results indicate that the specially calibrated correlations for hypersonic platform software can accurately predict the onset and length of transition region in low speed cases, and high Mach number correction shows good performance in hypersonic simulations.