Abstract: Due to the close proximity of super high-rise buildings in densely populated urban centers, the significant impact of wind-induced interference on adjacent structures must be taken into consideration. Previous research did not employ two aeroelastic models to investigate the wind-induced interference effect between two adjacent super-tall buildings. As a result, the aeroelastic effect and wind-induced interference effect could not be well reflected. In this paper, based on a series of two-aeroelastic-model wind tunnel tests, the aerodynamic interference effect of the across-wind response of two adjacent square high-rise buildings is studied. The influences of interference location, reduced wind speed (U_r), dynamic characteristics, and model type on the aerodynamic interference factors (I_IF) of across-wind acceleration response are analyzed. The wind tunnel tests were conducted at 35 interference locations, with 18 reduced wind speeds tested at each location, and contour maps of the interference factors were obtained. ‌The results show that, in tandem arrangements, I_IF reaches 1.1–1.3 at U_r=7–8 and U_r>14, with higher I_IF observed when the downstream disturbing building is closer to the target building; in side-by-side arrangements, I_IF rises to 1.2–1.3 near U_r=8 due to the narrow gap effect when the spacing exceeds twice the building width, while closer spacing suppresses the response as the two buildings behave as a single entity; in oblique upstream arrangements, the target building is significantly affected by the high-speed wake vortices of the disturbing building, with I_IF reaching 1.6–2.0 at high reduced wind speeds.‌ Subsequently, wind tunnel tests are performed on a one-rigid-one-aeroelastic building model at typical interference locations. Upon comparing the results of two kinds of wind tunnel tests, it was found that the aeroelastic effect increases the absolute negative aerodynamic damping of disturbed buildings at medium and high wind speeds, and the interference factor also increases. Neglecting the aerodynamic effect of disturbing buildings can bias the evaluation results of wind-induced response towards danger.